q-space diffusion of myelin-deficient spinal cords
نویسندگان
چکیده
منابع مشابه
High b-value q-space diffusion MRI in myelin-deficient rat spinal cords.
In this study, we explore the effect of the lack of myelin on the diffusion characteristics and diffusion anisotropy obtained from high b-value q-space diffusion-weighted MRI (q-space DWI) in excised rat spinal cords. Twenty-one-day-old myelin-deficient (md) mutant (N=6) and control rats (N=6) were used in this study. The MRI protocol included multi-slice T(1), T(2), proton density (PD) MR imag...
متن کاملDiffusion anisotropy in WM depends on myelin content in a diffusion time-dependent manner: evidence from high b value q-space diffusion MR of myelin deficient rat spinal cord
Synopsis The relative importance of myelin in the determining diffusion anisotropy of water in white matter (WM) remains elusive. To address this problem, high b value q-space diffusion MRS and MRI were performed on myelin deficient (md) and age-matched control spinal cords at different diffusion times and gradient pulse durations. Although differences in the diffusion characteristics between t...
متن کاملThe effect of myelin on the q-space and conventional DTI indices in excised myelin-deficient rat brains
Introduction Water diffusion in neuronal tissues was found to be anisotropic more than a decade ago and has been heavily exploited since by diffusion tensor imaging (DTI) to map white matter tracks in the brain. The widely used DTI techniques are based upon the analysis of a single diffusing component although it is well known that at sufficient high diffusion weighting, more than one diffusion...
متن کاملMyelin visualization using q-space MRI
K. Hikishima, K. Fujiyoshi, M. Yamada, Y. Komaki, S. Momoshima, K. Yagi, N. Tamaoki, Y. Toyama, M. Nakamura, and H. Okano Central Institute for Experimental Animals, Kasawaki, Kanagawa, Japan, Department of Physiology, Keio University, Department of Orthopaedic Surgery, Keio University, School of Health Science, Fujita Health University, Department of Radiology, Keio University, Graduate School...
متن کاملGangliosides of human, cat, and rabbit spinal cords and cord myelin.
Gangliosides were isolated from whole spinal cords and cord myelin of human, cat, and rabbit by a revised methodology. The method included the sequential application of DEAE-Sephadex column chromatography, base treatment, Sephadex G-50 column chromatography, and finally Iatrobeads column chromatography. The human whole spinal cord was found to contain about one-tenth of the ganglioside concentr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Magnetic Resonance in Medicine
سال: 2007
ISSN: 0740-3194,1522-2594
DOI: 10.1002/mrm.21389